000			02393cam a22002897a 4500
001			17654104
003			OSt
005			20160530115548.0
008			130311s2013 enka b 001 0 eng d
010			_a 2012538816
020			_a9780123878298
020			_a0123878292
035			_a(OCoLC)ocn714729532
040			_aSEKU
042			_alccopycat
050	0	0	_aRC 930.4 _b.G46 2013
245	0	0	_aGenetics of bone biology and skeletal disease / _cedited by Rajesh V. Thakker ... [et al.].
260			_aLondon ; _aWaltham, MA : _bAcademic Press, _c2013.
300			_axi, 621 p., [14] p. of col. plates : _bill. (some col.) ; _c28 cm.
504			_aIncludes bibliographical references and index.
520			_aThis book identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluations of treatments. The book is aimed at all students of bone biology and genetics, and with this in mind, it includes general introductory chapters on genetics and bone biology and more specific disease-orientated chapters, which comprehensively summarize the clinical, genetic, molecular genetic, animal model, functional and molecular pathology, diagnostic, counselling and treatment aspects of each disorder. Saves academic, medical, and pharma researchers time in quickly accessing the very latest details on a broad range of genetic bone issues, as opposed to searching through thousands of journal articles. Provides a common language for bone biologists and geneticists to discuss the development of bone cells and genetics and their interactions in the development of disease Researchers in all areas bone biology and genetics will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays. For those clinical researchers who are also MDs, correct diagnosis (and therefore correct treatment) of bone diseases depends on a strong understanding of the molecular basis for the disease-- _cSource other than Library of Congress.
650		0	_aBones _xDiseases _xGenetic aspects.
650	1	2	_aBone Diseases _xgenetics.
700	1		_aThakker, R. V.
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy1606/2012538816-d.html
942			_2lcc _cGEN
999			_c14828 _d14828